| Date | Home | Away | Result |
|---|---|---|---|
| 10/24/25 1:30 PM | SD Huesca | UD Las Palmas | 1-1 |
| 10/25/25 7:00 AM | CyD Leonesa | AD Ceuta FC | 0-1 |
| 10/25/25 9:15 AM | SD Eibar | CD Leganes | 0-0 |
| 10/25/25 9:15 AM | Albacete Balompie | Cordoba CF | 1-3 |
| 10/25/25 11:30 AM | FC Granada | FC Cadiz | 0-0 |
| 10/25/25 11:30 AM | Burgos CF | Real Sociedad B | 1-0 |
| 10/25/25 2:00 PM | CD Mirandes | Racing Santander | 1-3 |
| 10/26/25 8:00 AM | FC Malaga | Andorra CF | 4-1 |
| 10/26/25 12:30 PM | Sporting Gijon | Real Saragossa | 1-0 |
| 10/26/25 12:30 PM | UD Almeria | CD Castellon | 1-0 |
| 10/26/25 3:00 PM | Deportivo La Coruna | Real Valladolid | 1-1 |